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:''See also:Radiofrequency ablation (thyroid)'' Radiofrequency ablation (RFA) is a medical procedure in which part of the electrical conduction system of the heart, tumor or other dysfunctional tissue is ablated using the heat generated from medium frequency alternating current (in the range of 350–500 kHz). RFA is generally conducted in the outpatient setting, using either local anesthetics or conscious sedation anesthesia. Two important advantages of RF current (over previously used low frequency AC or pulses of DC) are that it does not directly stimulate nerves or heart muscle and therefore can often be used without the need for general anesthetic, and that it is very specific for treating the desired tissue without significant collateral damage. Documented benefits have led to RFA becoming widely used during the last 15 years.〔http://www.americanheart.org/presenter.jhtml?identifier=4682〕〔http://www.mayoclinic.org/radiofrequency-ablation〕 RFA procedures are performed under image guidance (such as X-ray screening, CT scan or ultrasound) by an interventional pain specialist (such as an anesthesiologist), interventional radiologist, otolaryngologists, a gastrointestinal or surgical endoscopist, or a cardiac electrophysiologist, a subspecialty of cardiologists. ==Tumors== RFA may be performed to treat tumors in the lung,〔(Results of radiofrequency ablation treatment of stage I non-small cell lung cancer: a prospective intention-to-treat study )〕〔(NHS, June 2008 - Radiofrequency ablation for lung cancer )〕〔(Daily Telegraph - June 2008 - Lung cancer radiation treatment offers new hope )〕 liver,〔 (BBC News- 16 January 2009 - Liver tumours 'microwaved away' )〕 kidney, and bone, as well as other body organs less commonly. Once the diagnosis of tumor is confirmed, a needle-like RFA probe is placed inside the tumor. The radiofrequency waves passing through the probe increase the temperature within tumor tissue and results in destruction of the tumor. RFA can be used with small tumors, whether these arose within the organ (primary tumors) or spread to the organ (metastases). The suitability of RFA for a particular tumor depends on multiple factors. RFA can usually be administered as an out-patient procedure, though may at times require a brief hospital stay. RFA may be combined with locally-delivered chemotherapy to treat hepatocellular carcinoma (primary liver cancer). A method currently in phase III trials uses the low-level heat (hyperthermia) created by the RFA probe to trigger release of concentrated chemotherapeutic drugs from heat-sensitive liposomes in the margins around the ablated tissue as a treatment for Hepatocellular carcinoma (HCC).〔(Phase 3 Study of ThermoDox With Radiofrequency Ablation (RFA) in Treatment of Hepatocellular Carcinoma (HCC) )〕 Radiofrequency ablation is also used in pancreatic cancer and bile duct cancer.〔 〕 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「radiofrequency ablation」の詳細全文を読む スポンサード リンク
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